The Role of Daruharidra as Pramehaghna Karma with Special Reference to Madhumeha

There are many drugs described in Ayurveda which can be used the treatment of ,Madhumeha. Sometime different species that particular drug is sold market having no therapeutic use or record potential under same vernacular name. In this study Daruharidra has been selected. The exact botanical source root Berberis aristata D.C, but more than 13 berberis available throughout Himalayan region ranging from 3,000-13,000ft height. One it asiatica, considered as a substitute B.aristata such scientific work done to prove it. Secondly now days due ban uprooting Daruharidra, physician started using stem. So, studystem ofboth assessed for its efficacy Prameha. D.C group 14 patients completed regime, highly significant (P<0.001 relief was seen Prabhutamutratrata(83.47%), Kar-pad-tal dah(86.40%) and Daurbalyata(62.50%) postprandial blood sugar significantly reduced (P<0.05). 14.28% patient markedly improved, 57.14% improved 28.57% were unchanged category. B.asiatica schedule, significant(P<0.001) observed prabhutamutrata (59.02%) dah(62.71%) post-prandial level (P<0.05).As overall effect concern 07.14% controlled,14.28% improved,57.14% 21.42% No difference therapeutical D.C. asiaticaRoxb.ex.D.C clinically. As pharmacological Clinical not much both drugs, water soluble extractive Berberine quantity higher groups so preparation Rasanjan other products.